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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1991-7-16
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pubmed:abstractText |
The assignment of paternity when the alleged father has died is now possible by use of a variety of allele-specific oligonucleotides after amplification of genomic DNA by the polymerase chain reaction (PCR). Issues relating to the inheritance of estates may be decided on fact rather than allegation. PCR-based genotyping of DQ alpha haplotypes from paraffin-embedded tissue of the deceased was used to prove non-paternity in the case reported here. Because the child was female, it was also possible to confirm the exclusion by using a second polymorphic site located in the factor VIII gene on the X chromosome.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0041-1132
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
441-2
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1675501-Alleles,
pubmed-meshheading:1675501-Deoxyribonucleases, Type II Site-Specific,
pubmed-meshheading:1675501-Factor VIII,
pubmed-meshheading:1675501-Female,
pubmed-meshheading:1675501-Genotype,
pubmed-meshheading:1675501-HLA-DQ Antigens,
pubmed-meshheading:1675501-Humans,
pubmed-meshheading:1675501-Infant, Newborn,
pubmed-meshheading:1675501-Male,
pubmed-meshheading:1675501-Oligonucleotide Probes,
pubmed-meshheading:1675501-Paternity,
pubmed-meshheading:1675501-Polymerase Chain Reaction,
pubmed-meshheading:1675501-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:1675501-X Chromosome
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pubmed:year |
1991
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pubmed:articleTitle |
Polymerase chain reaction and allele-specific oligonucleotides in paternity testing of the deceased.
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pubmed:affiliation |
Department of Pathology, University of Vermont, Burlington.
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pubmed:publicationType |
Journal Article
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