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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-6-2
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pubmed:abstractText |
A relatively small number of functional imaging studies of attention deficit hyperactivity disorder (ADHD) have shown abnormal prefrontal and striatal brain activation during tasks of motor response inhibition. However, the potential confound of previous medication exposure has not yet been addressed, and no functional imaging study exists to date on medication-naive children and adolescents with ADHD. The aim of this study was to investigate the neural substrates of a range of motor and cognitive inhibitory functions in a relatively large group of children and adolescents with ADHD who had never previously been exposed to medication.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0002-953X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
163
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1044-51
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pubmed:dateRevised |
2007-8-13
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pubmed:meshHeading |
pubmed-meshheading:16741205-Adolescent,
pubmed-meshheading:16741205-Attention Deficit Disorder with Hyperactivity,
pubmed-meshheading:16741205-Brain Mapping,
pubmed-meshheading:16741205-Central Nervous System Stimulants,
pubmed-meshheading:16741205-Cerebral Cortex,
pubmed-meshheading:16741205-Child,
pubmed-meshheading:16741205-Cognition Disorders,
pubmed-meshheading:16741205-Humans,
pubmed-meshheading:16741205-Inhibition (Psychology),
pubmed-meshheading:16741205-Magnetic Resonance Imaging,
pubmed-meshheading:16741205-Male,
pubmed-meshheading:16741205-Motor Skills,
pubmed-meshheading:16741205-Neuropsychological Tests,
pubmed-meshheading:16741205-Parietal Lobe,
pubmed-meshheading:16741205-Prefrontal Cortex,
pubmed-meshheading:16741205-Psychomotor Performance,
pubmed-meshheading:16741205-Reaction Time,
pubmed-meshheading:16741205-Task Performance and Analysis,
pubmed-meshheading:16741205-Temporal Lobe
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pubmed:year |
2006
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pubmed:articleTitle |
Task-specific hypoactivation in prefrontal and temporoparietal brain regions during motor inhibition and task switching in medication-naive children and adolescents with attention deficit hyperactivity disorder.
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pubmed:affiliation |
Department of Child Psychiatry, Institute of Psychiatry, King's College, London, SE5 8AF, UK.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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