Source:http://linkedlifedata.com/resource/pubmed/id/16736513
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-6-22
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pubmed:abstractText |
Epithelial membrane protein 2 (EMP2) is an estrus-regulated tetraspan protein that is required for endometrial competence in blastocyst implantation. EMP2 controls surface levels of several classes of integrin and other cell-interaction molecules, and their trafficking to glycolipid-enriched lipid raft domains is important in receptor signaling. These features suggest that EMP2 may contribute to neoplastic traits of endometrial cancer. The objective of this study was to determine the prevalence of EMP2 expression in endometrial neoplasms and its clinical significance.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2006 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
90-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16736513-Adenocarcinoma,
pubmed-meshheading:16736513-Adult,
pubmed-meshheading:16736513-Aged,
pubmed-meshheading:16736513-Aged, 80 and over,
pubmed-meshheading:16736513-Disease-Free Survival,
pubmed-meshheading:16736513-Endometrial Neoplasms,
pubmed-meshheading:16736513-Female,
pubmed-meshheading:16736513-Humans,
pubmed-meshheading:16736513-Membrane Glycoproteins,
pubmed-meshheading:16736513-Middle Aged,
pubmed-meshheading:16736513-Pilot Projects,
pubmed-meshheading:16736513-Precancerous Conditions,
pubmed-meshheading:16736513-Prognosis,
pubmed-meshheading:16736513-Retrospective Studies,
pubmed-meshheading:16736513-Survival Rate
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pubmed:year |
2006
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pubmed:articleTitle |
Expression of epithelial membrane protein-2 is associated with endometrial adenocarcinoma of unfavorable outcome.
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pubmed:affiliation |
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at the University of California-Los Angeles, Los Angeles, California, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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