Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
2006-6-7
pubmed:abstractText
By applying atomic force microscope (AFM)-based force spectroscopy together with computational modeling in the form of molecular force-field simulations, we have determined quantitatively the actuation energetics of a synthetic motor-molecule. This multidisciplinary approach was performed on specifically designed, bistable, redox-controllable [2]rotaxanes to probe the steric and electrostatic interactions that dictate their mechanical switching at the single-molecule level. The fusion of experimental force spectroscopy and theoretical computational modeling has revealed that the repulsive electrostatic interaction, which is responsible for the molecular actuation, is as high as 65 kcal.mol(-1), a result that is supported by ab initio calculations.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-11090349, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-11340054, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-11412088, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-11982368, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-12004125, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-14759218, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-14999851, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-15031499, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-15031500, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-15604399, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-15654345, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-15998079, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-16092823, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-16551115, http://linkedlifedata.com/resource/pubmed/commentcorrection/16735470-347575
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
8583-8
pubmed:dateRevised
2010-9-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Evaluation of synthetic linear motor-molecule actuation energetics.
pubmed:affiliation
Department of Mechanical and Aerospace Engineering, Institute for Cell Mimetic Space Exploration, and California Nanosystems Institute, University of California, Los Angeles, CA 90095, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.