Source:http://linkedlifedata.com/resource/pubmed/id/16734692
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2006-5-31
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pubmed:abstractText |
A genome scan to detect quantitative trait loci (QTL) affecting body weight in chickens was conducted on 238 F(2) chickens from a reciprocal cross of Silky Fowl and White Plymouth Rock using 125 microsatellite markers covering 23 autosomes and the Z chromosome. Two types of QTL were considered: static QTL (SQ) and developmental QTL (DQ). Static QTL affected the body weight from hatch to time t, and DQ affected the body weight from time t-1 to time t. Six SQ and nine DQ were detected. Of these QTL, four reached a genome-wide significance of 5% or better, with SQ1 and DQ1 being the most significant QTL. Static QTL1 was on chromosome 1 between GCT0006 and MCW0106 and explained 4.05-9.80% of the phenotypic variation in body weights from 3 to 12 weeks of age. At 9, 10 and 11 weeks, the genome-wide significance thresholds of SQ1 were <1%. Developmental QTL1 was located on chromosome 1 between MCW0168 and GCT0006, and explained 2.75% of the phenotypic variation for body weight from week 7 to 8 with a genome-wide significance level <1%. The results suggest that body weight from hatch to time t and developmental growth from time t-1 to time t may involve two different sets of genes or gene actions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0268-9146
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
276-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16734692-Animals,
pubmed-meshheading:16734692-Body Weight,
pubmed-meshheading:16734692-Breeding,
pubmed-meshheading:16734692-Chickens,
pubmed-meshheading:16734692-Chromosomes,
pubmed-meshheading:16734692-Genomics,
pubmed-meshheading:16734692-Genotype,
pubmed-meshheading:16734692-Microsatellite Repeats,
pubmed-meshheading:16734692-Quantitative Trait Loci,
pubmed-meshheading:16734692-Regression Analysis,
pubmed-meshheading:16734692-Sequence Analysis, DNA
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pubmed:year |
2006
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pubmed:articleTitle |
A genome scan for quantitative trait loci associated with body weight at different developmental stages in chickens.
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pubmed:affiliation |
State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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