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rdf:type |
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lifeskim:mentions |
umls-concept:C0021965,
umls-concept:C0040160,
umls-concept:C0070122,
umls-concept:C0332307,
umls-concept:C0681842,
umls-concept:C0871261,
umls-concept:C1269683,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1882417,
umls-concept:C2911692
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pubmed:issue |
6
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|
pubmed:dateCreated |
2006-5-26
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pubmed:abstractText |
The determinants of response to antidepressant treatment in major depression are unknown at present. The aim of the present study was to establish whether response is predicted by Hypothalamus-Pituitary-Thyroid (HPT) axis parameters or by a recently discovered polymorphism in the enzyme type II deiodinase (DII), which catalyzes the production of T3 in the brain.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0804-4643
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pubmed:author |
pubmed-author:AppelhofBente CBC,
pubmed-author:BrouwerJantien PJP,
pubmed-author:FliersEricE,
pubmed-author:HoogendijkWitte J GWJ,
pubmed-author:HuyserJochananJ,
pubmed-author:PeetersRobin PRP,
pubmed-author:ScheneAart HAH,
pubmed-author:TijssenJan G PJG,
pubmed-author:Van DyckRichardR,
pubmed-author:VisserTheo JTJ,
pubmed-author:WiersingaWilmar MWM
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pubmed:issnType |
Print
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pubmed:volume |
154
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
819-25
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pubmed:meshHeading |
pubmed-meshheading:16728541-Adult,
pubmed-meshheading:16728541-Antidepressive Agents, Second-Generation,
pubmed-meshheading:16728541-Depressive Disorder, Major,
pubmed-meshheading:16728541-Female,
pubmed-meshheading:16728541-Humans,
pubmed-meshheading:16728541-Iodide Peroxidase,
pubmed-meshheading:16728541-Male,
pubmed-meshheading:16728541-Middle Aged,
pubmed-meshheading:16728541-Paroxetine,
pubmed-meshheading:16728541-Polymorphism, Genetic,
pubmed-meshheading:16728541-Thyrotropin
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pubmed:year |
2006
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pubmed:articleTitle |
Thyrotropin, but not a polymorphism in type II deiodinase, predicts response to paroxetine in major depression.
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pubmed:affiliation |
Department of Endocrinology, Academic Medical Center, The Netherlands. j.p.brouwer@amc.uva.nl
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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