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rdf:type |
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lifeskim:mentions |
umls-concept:C0021053,
umls-concept:C0030705,
umls-concept:C0035366,
umls-concept:C0039082,
umls-concept:C0086427,
umls-concept:C0162326,
umls-concept:C0332307,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0518656,
umls-concept:C1552599,
umls-concept:C1704787
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pubmed:issue |
7
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pubmed:dateCreated |
1991-5-6
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pubmed:abstractText |
Chronic fatigue immune dysfunction syndrome (CFIDS) is a recently recognized illness characterized by debilitating fatigue as well as immunological and neurological abnormalities [Straus, S.E. (1988) J. Inf. Dis. 157, 405-412]. Once thought to be caused by Epstein-Barr virus, it is now thought to have a different but unknown etiology. We evaluated 30 adult and pediatric CFIDS patients from six eastern states for the presence of human T-lymphotropic virus (HTLV) types I and II by Western immunoblotting, polymearse chain reaction, and in situ hybridization of blood samples. The majority of patients were positive for HTLV antibodies by Western blotting and for HTLV-II gag sequences by polymerase chain reaction and in situ hybridization. Twenty nonexposure healthy controls were negative in all assays. These data support an association between an HTLV-II-like virus and CFIDS.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-13637100,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2166084,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2300816,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2448875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2578266,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2579970,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2582407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2780312,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2787888,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2824604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2829679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2846617,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2849717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2849719,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2887984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2892990,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2896386,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2897549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-2984282,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-3003749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-3033337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-3198937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-3260086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-6304725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1672770-6981847
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2922-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:1672770-Adolescent,
pubmed-meshheading:1672770-Adult,
pubmed-meshheading:1672770-Base Sequence,
pubmed-meshheading:1672770-DNA, Viral,
pubmed-meshheading:1672770-Deltaretrovirus Antibodies,
pubmed-meshheading:1672770-Fatigue Syndrome, Chronic,
pubmed-meshheading:1672770-Gene Products, gag,
pubmed-meshheading:1672770-Human T-lymphotropic virus 2,
pubmed-meshheading:1672770-Humans,
pubmed-meshheading:1672770-Immune System Diseases,
pubmed-meshheading:1672770-Molecular Sequence Data,
pubmed-meshheading:1672770-Oligonucleotide Probes,
pubmed-meshheading:1672770-Polymerase Chain Reaction,
pubmed-meshheading:1672770-RNA, Messenger,
pubmed-meshheading:1672770-Reference Values
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pubmed:year |
1991
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pubmed:articleTitle |
Retroviral sequences related to human T-lymphotropic virus type II in patients with chronic fatigue immune dysfunction syndrome.
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pubmed:affiliation |
Wistar Institute, Philadelphia, PA 19104.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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