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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8744
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pubmed:dateCreated |
1991-4-25
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pubmed:abstractText |
Isolated glomeruli from Brown-Norway (RT1n) rat kidney were inoculated into the thymus of 6 incompatible Lewis (RT1(1] rats pretreated for 2 days with 40 mg/kg oral cyclosporin daily and given 2.5 mg/kg subcutaneous dexamethasone at inoculation. 10 days later the left kidney from the Brown-Norway donor used to prepare glomeruli was transplanted orthotopically to the Lewis (RT1(1] rat that had received intrathymic glomeruli. Donor-specific unresponsiveness allowed the renal allograft to survive indefinitely without further immunosuppression. 6 control Lewis rats treated as above except that medium alone was injected intrathymically rejected a renal allograft within 7-9 days.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
337
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
750-2
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1672390-Animals,
pubmed-meshheading:1672390-Cyclosporins,
pubmed-meshheading:1672390-Dexamethasone,
pubmed-meshheading:1672390-Diuresis,
pubmed-meshheading:1672390-Drug Administration Schedule,
pubmed-meshheading:1672390-Evaluation Studies as Topic,
pubmed-meshheading:1672390-Graft Survival,
pubmed-meshheading:1672390-Immune Tolerance,
pubmed-meshheading:1672390-Kidney Glomerulus,
pubmed-meshheading:1672390-Kidney Transplantation,
pubmed-meshheading:1672390-Male,
pubmed-meshheading:1672390-Random Allocation,
pubmed-meshheading:1672390-Rats,
pubmed-meshheading:1672390-Rats, Inbred Lew,
pubmed-meshheading:1672390-Thymus Gland,
pubmed-meshheading:1672390-Time Factors
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pubmed:year |
1991
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pubmed:articleTitle |
Kidney graft survival in rats without immunosuppressants after intrathymic glomerular transplantation.
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pubmed:affiliation |
Mario Negri Institute for Pharmacological Research, Bergamo, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|