Source:http://linkedlifedata.com/resource/pubmed/id/16723772
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2006-5-25
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pubmed:abstractText |
There is a growing interest in Gafchromic films for patient dosimetry in radiotherapy and in radiology. A new model (XR-QA) with high sensitivity to low dose was tested in this study. The response of the film to different x-ray beam energies (range 28-145 kVp with various filtrations, dose range 0-100 mGy) and to visible light was investigated, together with the after exposure darkening properties. Exposed films were digitized with a commercially available, optical flatbed scanner. A single functional form for dose versus net pixel value variation has been determined for all the obtained calibration curves, with a unique fit parameter different for each of the used x-ray beams. The film response was dependent on beam energy, with higher colour variations for the beams in the range 80-140 kVp. Different sources of uncertainties in dose measurements, governed by the digitalization process, the film response uniformity and the calibration curve fit procedure, have been considered. The overall one-sigma dose measurement uncertainty depended on the beam energy and decreased with increasing absorbed dose. For doses above 10 mGy and beam energies in the range 80-140 kVp the total uncertainty was less than 5%, whereas for the 28 kVp beam the total uncertainty at 10 mGy was about 10%. The post-exposure colour variation was not negligible in the first 24 h after the exposure, with a consequent increase in the calculated dose of about 10%. Results of the analysis of the sensitivity to visible light indicated that a short exposure of this film to ambient and scanner light during the measurements will not have a significant impact on the radiation dosimetry.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0031-9155
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2871-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16723772-Calibration,
pubmed-meshheading:16723772-Dose-Response Relationship, Radiation,
pubmed-meshheading:16723772-Film Dosimetry,
pubmed-meshheading:16723772-Humans,
pubmed-meshheading:16723772-Radiation Dosage,
pubmed-meshheading:16723772-Radiotherapy Dosage,
pubmed-meshheading:16723772-Radiotherapy Planning, Computer-Assisted,
pubmed-meshheading:16723772-Reproducibility of Results,
pubmed-meshheading:16723772-Sensitivity and Specificity,
pubmed-meshheading:16723772-Time Factors,
pubmed-meshheading:16723772-X-Ray Film,
pubmed-meshheading:16723772-X-Rays
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pubmed:year |
2006
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pubmed:articleTitle |
Dose and energy dependence of response of Gafchromic XR-QA film for kilovoltage x-ray beams.
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pubmed:affiliation |
Struttura Complessa Fisica Sanitaria, Azienda Ospedaliera San Giovanni Battista, Corso Bramante 88, 10126 Torino, Italy. orampado@molinette.piemonte.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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