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pubmed:abstractText |
Two biologically related factors, complement factor H (CFH) and C-reactive protein (CRP), have been associated with AMD. The Y402H variant of CFH is located within the binding site of CFH for CRP. Although plasma CRP levels have been related to AMD and plasma CRP levels are partly determined by genetic variation, there is no information on whether genetic variants in CRP are associated with AMD.
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pubmed:affiliation |
Division of Preventive Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, and Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02215, USA. dschaumberg@rics.bwh.harvard.edu
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