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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-5-25
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pubmed:abstractText |
A growing understanding of the molecular events in age-related macular degeneration (AMD) has lead to targeted therapies for a select group of patients with advanced AMD. Development of therapies for the earlier stages requires further elucidation of disease mechanisms. In this study, a proteomics approach was used to identify proteins that had altered content in human donor eyes with progression of AMD.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2280-90
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pubmed:dateRevised |
2010-6-17
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pubmed:meshHeading |
pubmed-meshheading:16723435-Adult,
pubmed-meshheading:16723435-Aged,
pubmed-meshheading:16723435-Aged, 80 and over,
pubmed-meshheading:16723435-Animals,
pubmed-meshheading:16723435-Blotting, Western,
pubmed-meshheading:16723435-Disease Progression,
pubmed-meshheading:16723435-Electrophoresis, Gel, Two-Dimensional,
pubmed-meshheading:16723435-Eye Proteins,
pubmed-meshheading:16723435-Female,
pubmed-meshheading:16723435-Humans,
pubmed-meshheading:16723435-Macular Degeneration,
pubmed-meshheading:16723435-Male,
pubmed-meshheading:16723435-Middle Aged,
pubmed-meshheading:16723435-Proteome,
pubmed-meshheading:16723435-Rats,
pubmed-meshheading:16723435-Rats, Inbred F344,
pubmed-meshheading:16723435-Retina,
pubmed-meshheading:16723435-Spectrometry, Mass, Matrix-Assisted Laser...
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pubmed:year |
2006
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pubmed:articleTitle |
The proteome of central and peripheral retina with progression of age-related macular degeneration.
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pubmed:affiliation |
Department of Biochemistry, University of Minnesota, Minneapolis 55455, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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