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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8743
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pubmed:dateCreated |
1991-4-18
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pubmed:abstractText |
19 patients with locally advanced or cutaneous metastatic breast cancer were treated with the topical vitamin D analogue calcipotriol 100 micrograms daily. 14 patients completed 6 weeks' treatment; 3 showed a 50% reduction in the bidimensional diameter of treated lesions and 1 other patient showed a minimal response. 2 patients became hypercalcaemic during treatment. In all patients who responded the tumours contained receptors for 1,25-dihydroxyvitamin D3, shown by immunocytochemistry.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0140-6736
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
337
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
701-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1672178-Administration, Topical,
pubmed-meshheading:1672178-Adult,
pubmed-meshheading:1672178-Aged,
pubmed-meshheading:1672178-Aged, 80 and over,
pubmed-meshheading:1672178-Breast Neoplasms,
pubmed-meshheading:1672178-Calcitriol,
pubmed-meshheading:1672178-Carcinoma,
pubmed-meshheading:1672178-Drug Administration Schedule,
pubmed-meshheading:1672178-Drug Evaluation,
pubmed-meshheading:1672178-Female,
pubmed-meshheading:1672178-Humans,
pubmed-meshheading:1672178-Hypercalcemia,
pubmed-meshheading:1672178-Middle Aged,
pubmed-meshheading:1672178-Receptors, Calcitriol,
pubmed-meshheading:1672178-Receptors, Estrogen,
pubmed-meshheading:1672178-Receptors, Steroid,
pubmed-meshheading:1672178-Skin Neoplasms
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pubmed:year |
1991
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pubmed:articleTitle |
Topical calcipotriol treatment in advanced breast cancer.
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pubmed:affiliation |
Department of Cellular and Molecular Sciences, St. George's Hospital Medical School, London.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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