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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-9-29
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pubmed:abstractText |
[N-methyl-11C]alpha-methylaminoisobutyric acid ([11C]MeAIB) is a promising positron emission tomography (PET) tracer for imaging hormonally regulated system A amino acid transport. Uptake of [11C]MeAIB is totally specific for amino acid transport since [11C]MeAIB is metabolically stable both extra- and intracellularly. The aim of this study was to measure cumulated radioactivity in different organs and estimate the absorbed radiation doses to humans with the Medical Internal Radiation Dosimetry (MIRD) method.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1619-7070
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1178-84
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pubmed:meshHeading |
pubmed-meshheading:16721566-Amino Acid Transport System A,
pubmed-meshheading:16721566-Carbon Radioisotopes,
pubmed-meshheading:16721566-Female,
pubmed-meshheading:16721566-Humans,
pubmed-meshheading:16721566-Male,
pubmed-meshheading:16721566-Metabolic Clearance Rate,
pubmed-meshheading:16721566-Middle Aged,
pubmed-meshheading:16721566-Molecular Probe Techniques,
pubmed-meshheading:16721566-Neoplasms,
pubmed-meshheading:16721566-Organ Specificity,
pubmed-meshheading:16721566-Radiation Dosage,
pubmed-meshheading:16721566-Radioisotope Dilution Technique,
pubmed-meshheading:16721566-Radiometry,
pubmed-meshheading:16721566-Radiopharmaceuticals,
pubmed-meshheading:16721566-Tissue Distribution,
pubmed-meshheading:16721566-beta-Alanine
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pubmed:year |
2006
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pubmed:articleTitle |
Human radiation dosimetry of [11C]MeAIB, a new tracer for imaging of system A amino acid transport.
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pubmed:affiliation |
Turku PET Centre, Turku University Hospital, P.O. Box 52, 20521, Turku, Finland. tuula.tolvanen@tyks.fi
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pubmed:publicationType |
Journal Article
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