Linked Life Data

16719624

Source:http://linkedlifedata.com/resource/pubmed/id/16719624

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2006-5-24
pubmed:abstractText
The neuropsychological substrate of scripts, routines which guide much of human behavior, is unclear. We propose a model of script comprehension characterized by the interaction of semantic knowledge for script content, and executive resources that organize this knowledge into goal directed behavior. We examined these neuropsychological components by asking participants with Alzheimer's disease (AD) and frontotemporal dementia (behavioral disorder/dysexecutive syndrome (BDD) and semantic dementia (SD) subtypes), to judge the coherence of four-phrase scripts. The BDD group detected significantly fewer sequencing errors than semantic errors; the AD and SD groups detected these errors with equal frequency. Independent semantic measures predicted both semantic and sequencing script errors, while executive measures predicted sequencing errors only. Findings support a multi-component model of script comprehension.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0894-4105
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2006 APA, all rights reserved.
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
307-18
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
How does the brain support script comprehension? A study of executive processes and semantic knowledge in dementia.
pubmed:affiliation
Cognitive Neuroscience Division, Sergievsky Center, Columbia University Medical Center, New York, NY 10032, USA. scosentino@sergievsky.cpmc.columbia.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, N.I.H., Extramural