|
pubmed:abstractText |
The adrenal gland may give rise to pheochromocytomas, which are catecholamine-producing tumors originating from the adrenal medulla, or to adrenocortical tumors, which derive from the adrenocortical cortex and may be secreting or not. The genetic mechanisms underlying the formation of these tumors include somatic mutations in susceptibility genes, especially in the familial forms, and allelic loss, especially in chromosome 1.
|
|
pubmed:affiliation |
Department of Biochemistry, CHU Nancy-Brabois, INSERM U724, allée du Morvan, 54511, Vandoeuvre les Nancy, France. b.namour@chu-nancy.fr
|
