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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-3-7
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pubmed:abstractText |
A catecholamine-induced dilated cardiomyopathy is reported in a patient with multiple endocrine neoplasia, type 3. A histologic and ultrastructural study has been undertaken in cardiac biopsy samples, together with determination of myocardial Ca++ and cellular membrane fatty acids. Contraction band necrosis of cardiocytes with supercontraction of sarcomeres progressing to myofibrolysis and increased levels of myocardial Ca++ have been found as morphologic and biochemical abnormalities, respectively. No lipoperoxidation of cellular membranes or an alpha-adrenergic mediated reduction of coronary supply could be recognized in the study. We indicate a receptor-mediated intracellular Ca++ overload as the main abnormality responsible for myocardial impairment.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
0012-3692
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
382-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1671211-Adrenal Gland Neoplasms,
pubmed-meshheading:1671211-Adult,
pubmed-meshheading:1671211-Calcium,
pubmed-meshheading:1671211-Cardiomyopathy, Dilated,
pubmed-meshheading:1671211-Catecholamines,
pubmed-meshheading:1671211-Fatty Acids,
pubmed-meshheading:1671211-Humans,
pubmed-meshheading:1671211-Male,
pubmed-meshheading:1671211-Multiple Endocrine Neoplasia,
pubmed-meshheading:1671211-Myocardium,
pubmed-meshheading:1671211-Pheochromocytoma,
pubmed-meshheading:1671211-Sarcomeres,
pubmed-meshheading:1671211-Thyroid Neoplasms
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pubmed:year |
1991
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pubmed:articleTitle |
Catecholamine-induced cardiomyopathy in multiple endocrine neoplasia. A histologic, ultrastructural, and biochemical study.
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pubmed:affiliation |
Institute of Cardiology and Internal Medicine, Catholic University, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Case Reports
|