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rdf:type |
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lifeskim:mentions |
|
|
pubmed:issue |
3
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pubmed:dateCreated |
1991-2-27
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pubmed:abstractText |
The v-erb A oncogene of avian erythroblastosis virus is derived from a host gene for a thyroid hormone receptor and is able to block differentiation of erythroid cells and modify the growth properties of fibroblasts. Unlike its host cell progenitor, the v-erb A protein is found in both cytoplasmic and nuclear fractions of the cell. I report here that the cytoplasmic form of the v-erb A protein is associated in a higher molecular weight complex with heat shock protein 90, the same polypeptide found in association with the unliganded steroid receptors and with the soluble forms of the src oncogene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0021-9258
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
266
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1456-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1671036-Animals,
pubmed-meshheading:1671036-Cell Nucleus,
pubmed-meshheading:1671036-Chickens,
pubmed-meshheading:1671036-Chromatography, Gel,
pubmed-meshheading:1671036-Cross-Linking Reagents,
pubmed-meshheading:1671036-Cytoplasm,
pubmed-meshheading:1671036-Electrophoresis, Gel, Two-Dimensional,
pubmed-meshheading:1671036-Heat-Shock Proteins,
pubmed-meshheading:1671036-Macromolecular Substances,
pubmed-meshheading:1671036-Molecular Weight,
pubmed-meshheading:1671036-Oncogene Proteins v-erbA,
pubmed-meshheading:1671036-Protein Binding,
pubmed-meshheading:1671036-Receptors, Thyroid Hormone,
pubmed-meshheading:1671036-Retroviridae Proteins, Oncogenic
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pubmed:year |
1991
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pubmed:articleTitle |
A subpopulation of the v-erb A oncogene protein, a derivative of a thyroid hormone receptor, associates with heat shock protein 90.
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pubmed:affiliation |
Department of Microbiology, University of California, Davis 95616.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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