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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0003308,
umls-concept:C0020923,
umls-concept:C0040880,
umls-concept:C0205195,
umls-concept:C0243072,
umls-concept:C0360390,
umls-concept:C0441655,
umls-concept:C0449445,
umls-concept:C1516769,
umls-concept:C1517004,
umls-concept:C1880157,
umls-concept:C2919063
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pubmed:issue |
1
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pubmed:dateCreated |
2006-7-10
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|
pubmed:abstractText |
To synthesize new antimycobacterial and antifungal drugs that act by binding to sterol 14alpha-demethylase (14DM) and to characterize the drug-target protein interactions using computer-based molecular simulations.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0305-7453
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
76-84
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16709593-Antifungal Agents,
pubmed-meshheading:16709593-Antitubercular Agents,
pubmed-meshheading:16709593-Candida,
pubmed-meshheading:16709593-Computer Simulation,
pubmed-meshheading:16709593-Imidazoles,
pubmed-meshheading:16709593-Microbial Sensitivity Tests,
pubmed-meshheading:16709593-Models, Chemical,
pubmed-meshheading:16709593-Models, Molecular,
pubmed-meshheading:16709593-Molecular Structure,
pubmed-meshheading:16709593-Mycobacterium tuberculosis,
pubmed-meshheading:16709593-Triazoles
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pubmed:year |
2006
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pubmed:articleTitle |
Antifungal and antimycobacterial activity of new imidazole and triazole derivatives. A combined experimental and computational approach.
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|
pubmed:affiliation |
Microbiology Laboratory, Department of Biomedical Sciences, University of Trieste I-34127 Trieste, Italy. banfi@dsb.units.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
