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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-5-19
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pubmed:abstractText |
Convection-enhanced delivery (CED) is a novel technique used to deliver agents to the brain parenchyma for treatment of neoplastic, infectious, and degenerative conditions. The purpose of this study was to determine if CED would provide a larger volume of distribution (Vd) of a radiolabeled monoclonal antibody (mAb) than a bolus injection.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1092-0684
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
E14
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16709019-Antibodies, Monoclonal,
pubmed-meshheading:16709019-Brain,
pubmed-meshheading:16709019-Brain Neoplasms,
pubmed-meshheading:16709019-Dose-Response Relationship, Drug,
pubmed-meshheading:16709019-Drug Administration Routes,
pubmed-meshheading:16709019-Drug Delivery Systems,
pubmed-meshheading:16709019-Glioblastoma,
pubmed-meshheading:16709019-Humans,
pubmed-meshheading:16709019-Immunotherapy,
pubmed-meshheading:16709019-Infusion Pumps,
pubmed-meshheading:16709019-Iodine Radioisotopes,
pubmed-meshheading:16709019-Magnetic Resonance Imaging,
pubmed-meshheading:16709019-Microinjections,
pubmed-meshheading:16709019-Neoplasm Recurrence, Local,
pubmed-meshheading:16709019-Stereotaxic Techniques,
pubmed-meshheading:16709019-Survival Rate,
pubmed-meshheading:16709019-Tenascin,
pubmed-meshheading:16709019-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:16709019-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies.
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pubmed:affiliation |
Department of Surgery (Neurosurgery), Duke University Medical Center, Durham, North Carolina 27710, USA. john.sampson@duke.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, N.I.H., Extramural
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