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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-5-18
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pubmed:abstractText |
An elevated plasma total homocysteine (tHcy) level is a risk factor for many clinical conditions, including vascular disease and venous thrombosis. The tHcy levels are partly determined by genetic factors. Extensive candidate gene studies have identified several genetic variants, including the MTHFR 677C>T, that influence tHcy levels, but so far only part of the genetic variation in tHcy can be explained.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1538-7933
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1303-7
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16706975-Adolescent,
pubmed-meshheading:16706975-Adult,
pubmed-meshheading:16706975-Aged,
pubmed-meshheading:16706975-Aged, 80 and over,
pubmed-meshheading:16706975-Chromosome Mapping,
pubmed-meshheading:16706975-Chromosomes, Human, Pair 12,
pubmed-meshheading:16706975-Chromosomes, Human, Pair 13,
pubmed-meshheading:16706975-Chromosomes, Human, Pair 16,
pubmed-meshheading:16706975-Female,
pubmed-meshheading:16706975-Genetic Linkage,
pubmed-meshheading:16706975-Genome, Human,
pubmed-meshheading:16706975-Genotype,
pubmed-meshheading:16706975-Homocysteine,
pubmed-meshheading:16706975-Humans,
pubmed-meshheading:16706975-Lod Score,
pubmed-meshheading:16706975-Male,
pubmed-meshheading:16706975-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:16706975-Middle Aged,
pubmed-meshheading:16706975-Pedigree,
pubmed-meshheading:16706975-Polymorphism, Genetic,
pubmed-meshheading:16706975-Quantitative Trait Loci
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pubmed:year |
2006
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pubmed:articleTitle |
A genome-wide linkage scan for homocysteine levels suggests three regions of interest.
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pubmed:affiliation |
Department of Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands. h.vermeulen@endo.umcn.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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