Linked Life Data

16706645

Source:http://linkedlifedata.com/resource/pubmed/id/16706645

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-5-18
pubmed:abstractText
The effect of age and caloric-restriction (CR) diet on mitochondrial DNA (mtDNA) content in different rat tissues was investigated. A decrease of the mtDNA content occurs with aging in liver and soleus muscle, whereas there is no age-related significant change of mtDNA content in brain. CR fully reverses the age-dependent loss of mtDNA in liver and soleus, whereas it results in a significant increase of mtDNA amount above the value of aged ad libitum fed rats in brain. These results further support the tissue-specific effect of CR, likely because of the different dependence of tissues on external nutrient uptake.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1549-1684
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-4
pubmed:dateRevised
2007-9-11
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Tissue-specific effect of age and caloric restriction diet on mitochondrial DNA content.
pubmed:affiliation
Department of Biochemistry and Molecular Biology, University of Bari, Bari, Italy. p.cassano@biologia.uniba.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't