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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-8-18
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pubmed:abstractText |
Positron emission tomography (PET) has been used mostly for the study of brain blood flow and metabolism in normal controls and in a variety of neurological and psychiatric conditions. With the appropriate radiotracers, PET also allows non-invasive imaging and quantification of a growing list of neuroreceptors. 11C-carfentanil and 11C-diprenorphine, 2 potent opiate ligands, have been used to label opiate receptors in vivo in man. Some advantages and limitations of this technique are discussed. PET is a unique tool that could help us understand, at the receptor level, some biochemical aspects of addiction to opiate drugs. Specific questions can be answered, but carefully designed protocols are required.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8967
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9-19
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1670391-Brain,
pubmed-meshheading:1670391-Brain Chemistry,
pubmed-meshheading:1670391-Diprenorphine,
pubmed-meshheading:1670391-Fentanyl,
pubmed-meshheading:1670391-Humans,
pubmed-meshheading:1670391-Receptors, Opioid,
pubmed-meshheading:1670391-Substance-Related Disorders,
pubmed-meshheading:1670391-Tomography, Emission-Computed
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pubmed:articleTitle |
Imaging opiate receptors in the human brain with positron emission tomography. Potential applications for drug addiction research.
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pubmed:affiliation |
Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21205.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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