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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-5-16
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pubmed:abstractText |
Transplant arteriosclerosis is the main cause of long-term failure after cardiac transplantation. Vascular rejection is thought to be due to intimal proliferation occurring in response to arterial wall immune-mediated injury. A low molecular weight fucan (LMWF) compound, a sulfated polysaccharide, has been demonstrated to increase plasma levels of stromal cell-derived factor 1 (SDF-1) and consequently to mobilize bone marrow-derived vascular progenitor cells (BMVPC). The aim of this study was to evaluate the capacity of LMWF to prevent coronary intimal proliferation in a rat cardiac allograft model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0966-3274
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
14-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16701171-Animals,
pubmed-meshheading:16701171-Cell Proliferation,
pubmed-meshheading:16701171-Coronary Artery Disease,
pubmed-meshheading:16701171-Fucose,
pubmed-meshheading:16701171-Growth Inhibitors,
pubmed-meshheading:16701171-Heart Transplantation,
pubmed-meshheading:16701171-Male,
pubmed-meshheading:16701171-Molecular Weight,
pubmed-meshheading:16701171-Muscle, Smooth, Vascular,
pubmed-meshheading:16701171-Polysaccharides,
pubmed-meshheading:16701171-Rats,
pubmed-meshheading:16701171-Rats, Inbred BN,
pubmed-meshheading:16701171-Rats, Inbred Lew,
pubmed-meshheading:16701171-Sulfuric Acid Esters,
pubmed-meshheading:16701171-Transplantation, Homologous,
pubmed-meshheading:16701171-Tunica Intima
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pubmed:year |
2006
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pubmed:articleTitle |
Low molecular weight fucan prevents transplant coronaropathy in rat cardiac allograft model.
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pubmed:affiliation |
Cardiac and Vascular Surgery Departments, Rouen University Hospital, France.
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pubmed:publicationType |
Journal Article
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