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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2006-5-16
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pubmed:abstractText |
Matrix metalloproteinases (MMPs) play an important role in inflammation and neoplastic invasion and metastasis. Little is known about the effects of MMP inhibitors on hepatic ischemia/reperfusion injury. The aim of this study is to examine the inhibitory effects of ONO-4817 (oral inhibitor of MMPs) in rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0039-6060
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
653-64
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16701099-Animals,
pubmed-meshheading:16701099-DNA Primers,
pubmed-meshheading:16701099-Disease Models, Animal,
pubmed-meshheading:16701099-Kinetics,
pubmed-meshheading:16701099-Liver Circulation,
pubmed-meshheading:16701099-Male,
pubmed-meshheading:16701099-Matrix Metalloproteinase 2,
pubmed-meshheading:16701099-Matrix Metalloproteinase 9,
pubmed-meshheading:16701099-Matrix Metalloproteinases,
pubmed-meshheading:16701099-Phenyl Ethers,
pubmed-meshheading:16701099-RNA, Messenger,
pubmed-meshheading:16701099-Rats,
pubmed-meshheading:16701099-Rats, Wistar,
pubmed-meshheading:16701099-Reperfusion Injury,
pubmed-meshheading:16701099-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16701099-Time Factors,
pubmed-meshheading:16701099-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:16701099-Tumor Necrosis Factor-alpha
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pubmed:year |
2006
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pubmed:articleTitle |
Hepatic ischemia/reperfusion injury is prevented by a novel matrix metalloproteinase inhibitor, ONO-4817.
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pubmed:affiliation |
Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Japan.
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pubmed:publicationType |
Journal Article
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