|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2006-6-16
|
|
pubmed:abstractText |
The apolipoprotein E (ApoE) epsilon4 allele is a well-documented genetic risk factor for Alzheimer's disease (AD). Its role, if any, in the progression of cognitive and functional impairment in AD has been the subject of discrepant reports in the literature. This study aimed to determine whether ApoE epsilon4 dose is related to the progression of cognitive and functional decline in AD patients by combined retrospective and prospective analyses.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1420-8008
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
22
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
73-82
|
|
pubmed:dateRevised |
2008-3-24
|
|
pubmed:meshHeading |
pubmed-meshheading:16699282-Activities of Daily Living,
pubmed-meshheading:16699282-Age of Onset,
pubmed-meshheading:16699282-Aged,
pubmed-meshheading:16699282-Alleles,
pubmed-meshheading:16699282-Alzheimer Disease,
pubmed-meshheading:16699282-Apolipoprotein E4,
pubmed-meshheading:16699282-Apolipoproteins E,
pubmed-meshheading:16699282-Cognition Disorders,
pubmed-meshheading:16699282-Disease Progression,
pubmed-meshheading:16699282-Education,
pubmed-meshheading:16699282-Female,
pubmed-meshheading:16699282-Genotype,
pubmed-meshheading:16699282-Humans,
pubmed-meshheading:16699282-Male,
pubmed-meshheading:16699282-Neuropsychological Tests,
pubmed-meshheading:16699282-Prospective Studies,
pubmed-meshheading:16699282-Retrospective Studies
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Apolipoprotein E epsilon4 allele is unrelated to cognitive or functional decline in Alzheimer's disease: retrospective and prospective analysis.
|
|
pubmed:affiliation |
Alzheimer's Disease Research Unit, Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
