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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-6-16
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pubmed:abstractText |
Many studies have shown that estrogen replacement therapy may improve cognitive function in women and reduce the risk of Alzheimer's disease (AD). Because most of the estrogen neuroprotective effect is mediated by receptors, we studied the associations between estrogen receptor alpha (ESR1) polymorphisms (PvuII and XbaI) and AD, and their interactions with apolipoprotein E (APOE) polymorphism and plasma levels.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1420-8008
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-72
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pubmed:dateRevised |
2008-3-24
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pubmed:meshHeading |
pubmed-meshheading:16699281-Aged,
pubmed-meshheading:16699281-Alzheimer Disease,
pubmed-meshheading:16699281-Apolipoprotein E4,
pubmed-meshheading:16699281-Apolipoproteins E,
pubmed-meshheading:16699281-DNA,
pubmed-meshheading:16699281-Estrogen Receptor alpha,
pubmed-meshheading:16699281-Female,
pubmed-meshheading:16699281-Genotype,
pubmed-meshheading:16699281-Haplotypes,
pubmed-meshheading:16699281-Humans,
pubmed-meshheading:16699281-Male,
pubmed-meshheading:16699281-Neuropsychological Tests,
pubmed-meshheading:16699281-Polymorphism, Genetic,
pubmed-meshheading:16699281-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16699281-Risk Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Association of estrogen receptor alpha (ESR1) PvuII and XbaI polymorphisms with sporadic Alzheimer's disease and their effect on apolipoprotein E concentrations.
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pubmed:affiliation |
Department of Genetics and Molecular Biology, University 'La Sapienza', Rome, Italy. Rosamaria.corbo@uniroma1.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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