|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1-2
|
|
pubmed:dateCreated |
2006-5-15
|
|
pubmed:abstractText |
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal tract. Surgery has been the only effective therapy. However, many patients still eventually die of disease recurrence. Chemotherapy and radiation therapy have been of limited value. Imatinib mesylate (Glivec) is an orally administered competitive inhibitor of tyrosine kinases associated with the KIT, ABL protein, licensed for the treatment of metastatic GIST since 2002 in Germany.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0257-2753
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 2006 S. Karger AG, Basel.
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
24
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
207-11
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:16699280-Adult,
pubmed-meshheading:16699280-Aged,
pubmed-meshheading:16699280-Aged, 80 and over,
pubmed-meshheading:16699280-Antineoplastic Agents,
pubmed-meshheading:16699280-Disease-Free Survival,
pubmed-meshheading:16699280-Female,
pubmed-meshheading:16699280-Follow-Up Studies,
pubmed-meshheading:16699280-Gastrointestinal Stromal Tumors,
pubmed-meshheading:16699280-Germany,
pubmed-meshheading:16699280-Humans,
pubmed-meshheading:16699280-Male,
pubmed-meshheading:16699280-Middle Aged,
pubmed-meshheading:16699280-Piperazines,
pubmed-meshheading:16699280-Protein-Tyrosine Kinases,
pubmed-meshheading:16699280-Pyrimidines,
pubmed-meshheading:16699280-Retrospective Studies,
pubmed-meshheading:16699280-Severity of Illness Index,
pubmed-meshheading:16699280-Survival Rate,
pubmed-meshheading:16699280-Treatment Outcome
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Treatment of gastrointestinal stromal tumor with imatinib mesylate: a retrospective single-center experience in Heidelberg.
|
|
pubmed:affiliation |
Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany. Bernd_Kasper@med.uni-heidelberg.de
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
