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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-6-26
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pubmed:abstractText |
Reactive oxygen species (ROS) contribute to the pathogenesis of myocardial hypertrophy. NADPH oxidase is a major source of ROS production. The small GTPase Rac1 mediates the activation of NADPH oxidase; however, the mechanism of Rac1 activation is incompletely understood.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorobenzenes,
http://linkedlifedata.com/resource/pubmed/chemical/Free Radicals,
http://linkedlifedata.com/resource/pubmed/chemical/Guanine Nucleotide Dissociation...,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA...,
http://linkedlifedata.com/resource/pubmed/chemical/Leucine,
http://linkedlifedata.com/resource/pubmed/chemical/NADPH Oxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxides,
http://linkedlifedata.com/resource/pubmed/chemical/rac1 GTP-Binding Protein,
http://linkedlifedata.com/resource/pubmed/chemical/rho guanine nucleotide...,
http://linkedlifedata.com/resource/pubmed/chemical/rosuvastatin
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
342-51
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pubmed:meshHeading |
pubmed-meshheading:16698001-Angiotensin II,
pubmed-meshheading:16698001-Animals,
pubmed-meshheading:16698001-Blotting, Western,
pubmed-meshheading:16698001-Cardiomegaly,
pubmed-meshheading:16698001-Cells, Cultured,
pubmed-meshheading:16698001-Fluorobenzenes,
pubmed-meshheading:16698001-Free Radicals,
pubmed-meshheading:16698001-Guanine Nucleotide Dissociation Inhibitors,
pubmed-meshheading:16698001-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:16698001-Immunoprecipitation,
pubmed-meshheading:16698001-Leucine,
pubmed-meshheading:16698001-Lipid Peroxidation,
pubmed-meshheading:16698001-Mice,
pubmed-meshheading:16698001-Mice, Inbred C57BL,
pubmed-meshheading:16698001-Myocardium,
pubmed-meshheading:16698001-NADPH Oxidase,
pubmed-meshheading:16698001-Protein Binding,
pubmed-meshheading:16698001-Pyrimidines,
pubmed-meshheading:16698001-RNA Interference,
pubmed-meshheading:16698001-Sulfonamides,
pubmed-meshheading:16698001-Superoxides,
pubmed-meshheading:16698001-rac1 GTP-Binding Protein
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pubmed:year |
2006
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pubmed:articleTitle |
Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy.
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pubmed:affiliation |
Klinik und Poliklinik für Innere Medizin III, Universität des Saarlandes, Homburg/Saar, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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