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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1975-9-22
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pubmed:abstractText |
Escherichia coli-induced renal ultrastructural changes were observed 4 hr after the intravenous injection of 2 times 10-minus 6 bacteria. The initial changes consisted of mitochondrial swelling followed by intracellular vacuolation, nuclear membrane dilation, and increased lysosomal phagocytic activity. Alterations in the appearance of proximal tubular lysosomes included a loss of osmiophilic staining properties. Many of the involved cells showed necrosis and can presumably act as a nidus for bacterial proliferation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0021-0005
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:166961-Animals,
pubmed-meshheading:166961-Cell Nucleus,
pubmed-meshheading:166961-Escherichia coli,
pubmed-meshheading:166961-Female,
pubmed-meshheading:166961-Inclusion Bodies,
pubmed-meshheading:166961-Kidney,
pubmed-meshheading:166961-Kidney Tubular Necrosis, Acute,
pubmed-meshheading:166961-Kidney Tubules, Distal,
pubmed-meshheading:166961-Kidney Tubules, Proximal,
pubmed-meshheading:166961-Lysosomes,
pubmed-meshheading:166961-Mitochondrial Swelling,
pubmed-meshheading:166961-Pyelonephritis,
pubmed-meshheading:166961-Rats
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pubmed:year |
1975
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pubmed:articleTitle |
Pathogenesis of pyelonephritis. Escherichia coli-induced renal ultrastructural changes.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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