pubmed-article:1669586 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1669586 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:1669586 | lifeskim:mentions | umls-concept:C0036098 | lld:lifeskim |
pubmed-article:1669586 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
pubmed-article:1669586 | lifeskim:mentions | umls-concept:C0039082 | lld:lifeskim |
pubmed-article:1669586 | lifeskim:mentions | umls-concept:C0332256 | lld:lifeskim |
pubmed-article:1669586 | lifeskim:mentions | umls-concept:C0082542 | lld:lifeskim |
pubmed-article:1669586 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:1669586 | pubmed:dateCreated | 1994-2-22 | lld:pubmed |
pubmed-article:1669586 | pubmed:abstractText | Minor labial salivary glands obtained at biopsy from patients with Sjögren's syndrome were investigated by immunomorphological methods for the presence of monocyte-derived macrophages. According to our observations published earlier the immunomorphological detection of factor XIII subunit a is a useful marker for recognizing cells of monocyte/macrophage lineage. Factor XIII subunit a was detected by a highly sensitive immunoperoxidase staining, and cells containing this coagulation enzyme were characterized by double immunofluorescence stainings. Factor XIII subunit a+ cells were found to be highly accumulated at the interface of normal tissue and peritubular infiltrate. In double immunofluorescence labelling systems factor XIII subunit a+ cells were simultaneously labelled by RFD7 and Dako-antimacrophage monoclonal antibodies. They also expressed HLA-DR antigen as revealed by a reaction with RFDR2 monoclonal antibody. The results suggest that monocyte-derived tissue macrophages are present in salivary glands of patients with Sjögren's syndrome and have a characteristic distribution. It can be assumed that they have a role in the demarcation of peritubular inflammation and thus have an effect on the progression of the disease. | lld:pubmed |
pubmed-article:1669586 | pubmed:language | eng | lld:pubmed |
pubmed-article:1669586 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1669586 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1669586 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1669586 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1669586 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1669586 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1669586 | pubmed:month | Aug | lld:pubmed |
pubmed-article:1669586 | pubmed:issn | 1018-9068 | lld:pubmed |
pubmed-article:1669586 | pubmed:author | pubmed-author:NagyGG | lld:pubmed |
pubmed-article:1669586 | pubmed:author | pubmed-author:SzegediGG | lld:pubmed |
pubmed-article:1669586 | pubmed:author | pubmed-author:AdányRR | lld:pubmed |
pubmed-article:1669586 | pubmed:author | pubmed-author:GómezRR | lld:pubmed |
pubmed-article:1669586 | pubmed:author | pubmed-author:ZeherMM | lld:pubmed |
pubmed-article:1669586 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1669586 | pubmed:volume | 1 | lld:pubmed |
pubmed-article:1669586 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1669586 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1669586 | pubmed:pagination | 261-5 | lld:pubmed |
pubmed-article:1669586 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:1669586 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:1669586 | pubmed:articleTitle | Macrophage containing factor XIII subunit a in salivary glands of patients with Sjögren's syndrome. | lld:pubmed |
pubmed-article:1669586 | pubmed:affiliation | 3rd Department of Medicine, University Medical School, Debrecen, Hungary. | lld:pubmed |
pubmed-article:1669586 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1669586 | lld:pubmed |