rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1975-10-11
|
pubmed:abstractText |
The effect of human interferon on single-cycle replication of Herpesvirus hominis type 1 (HV-1) and vesicular stomatitis virus (VSV) in human foreskin fibroblast cultures (HFF) was studied. After treatment of HFF cultures with low concentrations (58 U) of human interferon, a variable but statistically significant inhibition of HV-1 was observed. At higher concentrations (greater than 95 U) yield reduction of HV in interferon-treated cultures approached that of VSV. Preliminary data indicate that antiviral activity decays more rapidly for HV-1 than for VSV after removal of interferon from cultures.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0019-9567
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
104-8
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:166922-Animals,
pubmed-meshheading:166922-Culture Techniques,
pubmed-meshheading:166922-Eggs,
pubmed-meshheading:166922-Fibroblasts,
pubmed-meshheading:166922-Humans,
pubmed-meshheading:166922-Interferons,
pubmed-meshheading:166922-Kidney,
pubmed-meshheading:166922-Rabbits,
pubmed-meshheading:166922-Simplexvirus,
pubmed-meshheading:166922-Vesicular stomatitis Indiana virus,
pubmed-meshheading:166922-Viral Interference,
pubmed-meshheading:166922-Virus Cultivation,
pubmed-meshheading:166922-Virus Replication
|
pubmed:year |
1975
|
pubmed:articleTitle |
Inhibition of Herpesvirus hominis replication by human interferon.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|