Source:http://linkedlifedata.com/resource/pubmed/id/16689832
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2006-5-12
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pubmed:abstractText |
We here report a very rare case of female urethral adenocarcinoma. A 77-year-old woman presented with urinary retention. Cystoscopy showed a urethral tumor and the biopsy material showed adenocarcinoma. Macroscopically, the tumor measuring 3.0 x 3.0 x 2.4 cm was predominantly observed around the periurethral area on the proximal side. Histologically, patterns of columnar/mucinous adenocarcinoma, clear cell adenocarcinoma and papillary/micropapillary carcinoma were observed, but there was no evidence of a cribriform pattern. Immunohistochemically, neoplastic cells of at least one of three components were positive for CK7 and CK20 or CA125. We suggest that female urethral adenocarcinoma with a histologically and immunohistochemically heterogeneous phenotype may originate from cells within urethral or paraurethral tissue, such as urethritis glandularis or intestinal metaplastic epithelium and Mullerian tissue.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CA-125 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/KRT20 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/KRT7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Keratin-20,
http://linkedlifedata.com/resource/pubmed/chemical/Keratin-7,
http://linkedlifedata.com/resource/pubmed/chemical/Keratins
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0903-4641
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16689832-Adenocarcinoma,
pubmed-meshheading:16689832-Aged,
pubmed-meshheading:16689832-CA-125 Antigen,
pubmed-meshheading:16689832-Female,
pubmed-meshheading:16689832-Humans,
pubmed-meshheading:16689832-Immunochemistry,
pubmed-meshheading:16689832-Keratin-20,
pubmed-meshheading:16689832-Keratin-7,
pubmed-meshheading:16689832-Keratins,
pubmed-meshheading:16689832-Phenotype,
pubmed-meshheading:16689832-Urethral Neoplasms
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pubmed:year |
2006
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pubmed:articleTitle |
Female urethral adenocarcinoma with a heterogeneous phenotype.
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pubmed:affiliation |
Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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