Source:http://linkedlifedata.com/resource/pubmed/id/16687075
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2006-5-11
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| pubmed:abstractText |
Epstein-Barr virus (EBV) in nasopharyngeal carcinoma (NPC) cells expresses Epstein-Barr nuclear antigen 1 (EBNA1), latent membrane protein 1 (LMP1), and LMP2. LMP2 is an ideal target for immunotherapy because LMP2 mRNA is detected in 100% nasopharyngeal carcinoma cells and LMP2 protein shows stronger immunogenity than the rest 2 viral proteins. This study was to analyze the sequence of CTL epitopes in the transmembrane region of LMP2 to optimize LMP2-targeted immunotherapy.
|
| pubmed:language |
chi
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
1000-467X
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
566-9
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| pubmed:meshHeading |
pubmed-meshheading:16687075-Amino Acid Substitution,
pubmed-meshheading:16687075-Base Sequence,
pubmed-meshheading:16687075-Epitopes, T-Lymphocyte,
pubmed-meshheading:16687075-Epstein-Barr Virus Infections,
pubmed-meshheading:16687075-Herpesvirus 4, Human,
pubmed-meshheading:16687075-Humans,
pubmed-meshheading:16687075-Nasopharyngeal Neoplasms,
pubmed-meshheading:16687075-Respiratory Mucosa,
pubmed-meshheading:16687075-Sequence Analysis,
pubmed-meshheading:16687075-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:16687075-Viral Matrix Proteins
|
| pubmed:year |
2006
|
| pubmed:articleTitle |
[Sequence analysis of the CTL epitopes in transmembrane region of latent membrane protein 2 of Epstein-Barr virus derived from nasopharyngeal carcinoma cells].
|
| pubmed:affiliation |
State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China.
|
| pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|