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pubmed-article:16685738pubmed:abstractTextTunnel infection is an uncommon but serious complication observed in patients with partially implanted central venous catheters. International guidelines suggest that should include antibiotics and catheter removal. A success rate of only 5-20% was reported without catheter removal. We treated 13 episodes of tunnel Gram-positive bacterial infection occurring in pediatric patients with cancer or serious blood disorders with 24-hr intra-catheter antibiotic continuous infusion. This approach led to a 69% success rate. Continuous infusion might be an attractive option to treat tunnel Gram-positive bacterial infections when catheter removal might not be feasible or advisable.lld:pubmed
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pubmed-article:16685738pubmed:authorpubmed-author:MoroniCClld:pubmed
pubmed-article:16685738pubmed:authorpubmed-author:GiacchinoMMlld:pubmed
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pubmed-article:16685738pubmed:copyrightInfo2007 Wiley-Liss, Inclld:pubmed
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pubmed-article:16685738pubmed:volume49lld:pubmed
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pubmed-article:16685738pubmed:dateRevised2009-1-12lld:pubmed
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pubmed-article:16685738pubmed:year2007lld:pubmed
pubmed-article:16685738pubmed:articleTitleContinuous antibiotic infusion for salvage therapy of partially implanted central venous catheter tunnel infections due to staphylococci.lld:pubmed
pubmed-article:16685738pubmed:affiliationDepartment of Pediatrics, Regina Margherita Children's Hospital, Turin, Italy. mareva.giacchino@unito.itlld:pubmed
pubmed-article:16685738pubmed:publicationTypeJournal Articlelld:pubmed