| pubmed-article:16677927 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16677927 | lifeskim:mentions | umls-concept:C0031809 | lld:lifeskim |
| pubmed-article:16677927 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:16677927 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:16677927 | lifeskim:mentions | umls-concept:C0065749 | lld:lifeskim |
| pubmed-article:16677927 | lifeskim:mentions | umls-concept:C0302600 | lld:lifeskim |
| pubmed-article:16677927 | lifeskim:mentions | umls-concept:C0041618 | lld:lifeskim |
| pubmed-article:16677927 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:16677927 | pubmed:dateCreated | 2006-5-8 | lld:pubmed |
| pubmed-article:16677927 | pubmed:abstractText | Matrigel, a basement membrane extract, has been extensively used in in vivo angiogenesis. Contrast ultrasound imaging (CUI) of implanted Matrigel plugs with (+bFGF) and without basic fibroblast growth factor (-bFGF) was performed 7 and 14 d after implantation, followed by histologic analysis. Statistically significant differences between +bFGF and -bFGF plugs were apparent at d 7 in both plug size and contrast enhancement (both p < 0.05). Histopathology revealed differences in microvessel density (MVD) between +bFGF and -bFGF at d 7 and d 14. A significant correlation between MVD and both power Doppler contrast-enhanced area (r = 0.65, p < 0.05) and fraction of plug enhanced (r = 0.59, p < 0.05) was present. CUI of Matrigel plugs was shown to be a robust method for distinguishing between two different angiogenic states. Ultrasound measurements of blood flow in the plugs correlated with MVD, a histologic technique used to quantify tumor angiogenesis. | lld:pubmed |
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| pubmed-article:16677927 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:16677927 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:16677927 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16677927 | pubmed:month | May | lld:pubmed |
| pubmed-article:16677927 | pubmed:issn | 0301-5629 | lld:pubmed |
| pubmed-article:16677927 | pubmed:author | pubmed-author:WisnerErik... | lld:pubmed |
| pubmed-article:16677927 | pubmed:author | pubmed-author:FerraraKather... | lld:pubmed |
| pubmed-article:16677927 | pubmed:author | pubmed-author:DaytonPaul... | lld:pubmed |
| pubmed-article:16677927 | pubmed:author | pubmed-author:BlochSusannah... | lld:pubmed |
| pubmed-article:16677927 | pubmed:author | pubmed-author:StiegerSusann... | lld:pubmed |
| pubmed-article:16677927 | pubmed:author | pubmed-author:ForemanOdedO | lld:pubmed |
| pubmed-article:16677927 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16677927 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:16677927 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16677927 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16677927 | pubmed:pagination | 673-81 | lld:pubmed |
| pubmed-article:16677927 | pubmed:dateRevised | 2010-12-3 | lld:pubmed |
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| pubmed-article:16677927 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16677927 | pubmed:articleTitle | Ultrasound assessment of angiogenesis in a matrigel model in rats. | lld:pubmed |
| pubmed-article:16677927 | pubmed:affiliation | Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. smstieger@ucdavis.edu | lld:pubmed |
| pubmed-article:16677927 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16677927 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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