| pubmed-article:16677848 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C0220908 | lld:lifeskim |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C0034760 | lld:lifeskim |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C1257867 | lld:lifeskim |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C0179630 | lld:lifeskim |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C0182324 | lld:lifeskim |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C1139930 | lld:lifeskim |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C0560008 | lld:lifeskim |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C1705968 | lld:lifeskim |
| pubmed-article:16677848 | lifeskim:mentions | umls-concept:C1523987 | lld:lifeskim |
| pubmed-article:16677848 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:16677848 | pubmed:dateCreated | 2006-6-6 | lld:pubmed |
| pubmed-article:16677848 | pubmed:abstractText | In traditional screening with 96-well plates, microliters of substrates are consumed for each reaction. Further miniaturization is limited by the special equipment and techniques required to dispense nanoliter volumes of fluid. Plug-based microfluidics confines reagents in nanoliter plugs (droplets surrounded by fluorinated carrier fluid), and uses simple pumps to control the flow of plugs. By using cartridges pre-loaded with nanoliter plugs of reagents, only two pumps and a merging junction are needed to set up a screen. Screening with preloaded cartridges uses only nanoliters of substrate per reaction, and requires no microfabrication. The low cost and simplicity of this method has the potential of replacing 96-well and other multi-well plates, and has been applied to enzymatic assays, protein crystallization and optimization of organic reactions. | lld:pubmed |
| pubmed-article:16677848 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16677848 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16677848 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16677848 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16677848 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:16677848 | pubmed:issn | 1367-5931 | lld:pubmed |
| pubmed-article:16677848 | pubmed:author | pubmed-author:IsmagilovRust... | lld:pubmed |
| pubmed-article:16677848 | pubmed:author | pubmed-author:ChenDelai LDL | lld:pubmed |
| pubmed-article:16677848 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16677848 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:16677848 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16677848 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16677848 | pubmed:pagination | 226-31 | lld:pubmed |
| pubmed-article:16677848 | pubmed:dateRevised | 2010-12-3 | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:meshHeading | pubmed-meshheading:16677848... | lld:pubmed |
| pubmed-article:16677848 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16677848 | pubmed:articleTitle | Microfluidic cartridges preloaded with nanoliter plugs of reagents: an alternative to 96-well plates for screening. | lld:pubmed |
| pubmed-article:16677848 | pubmed:affiliation | Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA. | lld:pubmed |
| pubmed-article:16677848 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16677848 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:16677848 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16677848 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16677848 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16677848 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16677848 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16677848 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16677848 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16677848 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16677848 | lld:pubmed |
