Linked Life Data

16674203

Source:http://linkedlifedata.com/resource/pubmed/id/16674203

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-5-5
pubmed:abstractText
We establish, for the first time, a simulation model for dealing with the second-harmonic signals under a microscope through a tissue-like turbid medium, based on the Monte Carlo method. With this model, the angle-resolved distribution and the signal level eta of second-harmonic light through a slab of the turbid medium are demonstrated and the effects of the thickness (d) of the turbid medium, the numerical aperture (NA) of the objective as well as the size (rho) of the scatterers forming the turbid medium are explored. Simulation results reveal that the use of a small objective NA results in a narrow angle distribution but strong second-harmonic signals. A turbid medium consisting of large scattering particles has a strong influence on the angle distribution and the signal level eta, which results in a low penetration limit for second-harmonic signals made up of ballistic photons. It is approximately 30 microm in our situation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1083-3668
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
024013
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Simulation study of second-harmonic microscopic imaging signals through tissue-like turbid media.
pubmed:affiliation
South China Normal University, School for Information and Optoelectronic Science & Engineering, Laboratory of Photonic Chinese Medicine, Shipai, Guangzhou, China, 510631. xiaoyuandeng@yahoo.com.cn
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't