Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-6-5
pubmed:abstractText
XMyoD is the earliest marker of muscle development in Xenopus embryos and is expressed in presumptive somites in the late gastrula. In the early gastrula, in situ hybridization showed XMyoD transcripts in precursors of both muscle and non-muscle mesoderm. Embryos ventralized by UV irradiation made no muscle, but expressed XMyoD transiently. Embryo explants that differentiated ventral mesoderm also expressed XMyoD transiently. These results show that the initiation of XMyoD expression is not sufficient to convert cells to muscle and suggest that XMyoD is expressed in response to a general mesodermalizing signal; expression is stabilized and enhanced only in muscle precursors that have received a dorsalizing signal.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0950-1991
pubmed:author
pubmed:issnType
Print
pubmed:volume
113
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1387-93
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Transient expression of XMyoD in non-somitic mesoderm of Xenopus gastrulae.
pubmed:affiliation
Department of Molecular and Cellular Biology, University of California, Berkeley 94720.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't