Linked Life Data

16672925

Source:http://linkedlifedata.com/resource/pubmed/id/16672925

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2006-6-27
pubmed:abstractText
Despite its apparent simplicity, the nematode worm Caenorhabditis elegans has developed into an important model for biomedical research, particularly in the functional characterization of novel drug targets that have been identified using genomics technologies. The cellular complexity and the conservation of disease pathways between C. elegans and higher organisms, together with the simplicity and cost-effectiveness of cultivation, make for an effective in vivo model that is amenable to whole-organism high-throughput compound screens and large-scale target validation. This review describes how C. elegans models can be used to advance our understanding of the molecular mechanisms of drug action and disease pathogenesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1474-1776
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
387-98
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Finding function in novel targets: C. elegans as a model organism.
pubmed:affiliation
Devgen, Technologie-park 30, B-9052 Gent, Belgium. titus.kaletta@devgen.com
pubmed:publicationType
Journal Article, Review