Linked Life Data

1666902

Source:http://linkedlifedata.com/resource/pubmed/id/1666902

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-5-13
pubmed:abstractText
The effects of adrenaline and isoprenaline on K+ contractures of curarized tonic skeletal fibers were investigated. The K+ contractures of tonic fibers have a peak tension followed by a sustained tension. The peak tension and total tension (the tension-time integral--area--of K+ contractures) were increased by adrenaline and isoprenaline. The resting potential of tonic skeletal fibers were unaffected by adrenaline. The calcium channel blocker (cadmium and nifedipine) greatly blocked the effects of adrenaline on the peak and total tension of K+ contractures. On the other hand, the peak and sustained tensions of K+ contractures were greatly reduced in Ca(2+)-free solution, but, the peak tension recovered when the fibers were pre-incubated in adrenaline. It is proposed that adrenergic modulation of tension in tonic skeletal muscle fibers could be related with the modulation of Ca2+ channels and/or Ca2+ release from the sarcoplasmic reticulum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-521X
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
851-60
pubmed:dateRevised
2007-3-21
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Adrenergic modulation of the K+ contractures in tonic skeletal muscle fibers of the frog.
pubmed:affiliation
Centro Universitario de Investigaciones Biomedicas, Universidad de Colima, Mexico.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't