Source:http://linkedlifedata.com/resource/pubmed/id/16668250
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
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| pubmed:dateCreated |
2010-6-29
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| pubmed:abstractText |
A radiation-induced mutant of Scotch spearmint (Mentha x gracilis) was shown to produce an essential oil containing principally C3-oxygenated p-menthane monoterpenes that are typical of peppermint, instead of the C6-oxygenated monoterpene family characteristic of spearmint. In vitro measurement of all of the enzymes responsible for the production of both the C3-oxygenated and C6-oxygenated families of monoterpenes from the common precursor (-)-limonene indicated that a virtually identical complement of enzymes was present in wild type and mutant, with the exception of the microsomal, cytochrome P-450-dependent (-)-limonene hydroxylase; the C6-hydroxylase producing (-)-trans-carveol in the wild type had been replaced by a C3-hydroxylase producing (-)-trans-isopiperitenol in the mutant. Additionally, the mutant, but not the wild type, could carry out the cytochrome P-450-dependent epoxidation of the alpha,beta-unsaturated bond of the ketones formed via C3-hydroxylation. Although present in the wild type, the enzymes of the C3-pathway that convert trans-isopiperitenol to menthol isomers are synthetically inactive because of the absence of the key C3-oxygenated intermediate generated by hydroxylation of limonene. These results, which clarify the origins of the C3- and C6-oxygenation patterns, also allow correction of a number of earlier biogenetic proposals for the formation of monoterpenes in Mentha.
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| pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-13211401,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-16662335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-16666709,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-17262485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-2297225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-2991702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-3243859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-3429507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-3619014,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-3755881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-3885858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-6326392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16668250-6830247
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:month |
Jul
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| pubmed:issn |
0032-0889
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
96
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
744-52
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| pubmed:dateRevised |
2010-9-15
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| pubmed:year |
1991
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| pubmed:articleTitle |
Biochemical characterization of a spearmint mutant that resembles peppermint in monoterpene content.
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| pubmed:affiliation |
Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164-6340.
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| pubmed:publicationType |
Journal Article
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