Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1992-5-6
pubmed:abstractText
Response of the ATP, ubiquitin-dependent system during the enhanced degradation of erythrocyte maturation conforms to the general regulatory features common to several similar but unrelated systems. In erythroid cells enhanced degradation follows three phases: (1) Onset of degradation characterized by an increase in the intracellular concentration of free and conjugated ubiquitin, brought about by reduction in mean cell volume; (2) Active enhanced degradation during cellular remodeling; and (3) Loss of activity as a consequence of spontaneous inactivation of components required for ubiquitin conjugation. The extent of degradative remodeling is probably functionally limited by the loss of these critical ligation enzymes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-2598
pubmed:author
pubmed:issnType
Print
pubmed:volume
307
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-205
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Ubiquitin-mediated processes in erythroid cell maturation.
pubmed:affiliation
Department of Biochemistry, Medical College of Wisconsin, Milwaukee.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review