|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1992-4-8
|
|
pubmed:abstractText |
Immunochemical study of blood sera from mice immunized with rabbit immunoglobulins (AT1) to herpes simplex virus type I (HSV-I) detected antiidiotypic antibodies AT2 in five of them (antiID). The affinity-purified antiID were shown to induce in syngeneic mice production of antibody (AT3) interacting with HSV-I antigen. In vitro, antiID (AT3) were shown to neutralize the virus activity. Analysis of the results suggests that the antiID imitate the antigenic properties of HSV-I and can induce specific immune response.
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|
pubmed:language |
rus
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0507-4088
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
36
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
312-5
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:1665620-Animals,
pubmed-meshheading:1665620-Antibodies, Anti-Idiotypic,
pubmed-meshheading:1665620-Antibodies, Viral,
pubmed-meshheading:1665620-Chromatography, Affinity,
pubmed-meshheading:1665620-Complement Fixation Tests,
pubmed-meshheading:1665620-Immunization,
pubmed-meshheading:1665620-Immunoenzyme Techniques,
pubmed-meshheading:1665620-Mice,
pubmed-meshheading:1665620-Mice, Inbred BALB C,
pubmed-meshheading:1665620-Neutralization Tests,
pubmed-meshheading:1665620-Rabbits,
pubmed-meshheading:1665620-Simplexvirus
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|
pubmed:articleTitle |
[Anti-idiotypic antibodies to the herpes simplex type-1 virus neutralize the virus' infectious activity].
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|
pubmed:publicationType |
Journal Article,
English Abstract
|
