Linked Life Data

16649214

Source:http://linkedlifedata.com/resource/pubmed/id/16649214

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2006-8-21
pubmed:abstractText
Oral squamous cell carcinoma is a disfiguring, highly invasive and metastatic cancer. Despite advances in detection and therapy, many patients will continue to face a poor prognosis. It is well established that the predominate factor determining overall survival in patients with oral squamous cell carcinoma is lymph node involvement. Tumor growth and progression to invasive cancer requires tumor cell interactions with the extracellular matrix. An understanding of how the extracellular matrix influences tumor development and invasion is fundamental in the development of new prognostic indicators and treatment strategies for oral squamous cell carcinoma. In this review, we summarize how changes in the extracellular matrix contribute to oral cancer development.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1043-3074
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
740-9
pubmed:dateRevised
2007-12-3
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
The extracellular matrix in oral squamous cell carcinoma: friend or foe?
pubmed:affiliation
Department of Otorhinolaryngology-Head and Neck Surgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, 5 Ravdin Building, Philadelphia PA 19104, USA. bziober@mail.med.upenn.edu
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural