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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1992-3-26
|
| pubmed:abstractText |
Phosphorylation of the bovine brain TTX-sensitive cytosolic protein which is similar in several functional properties to the membrane potential-dependent sodium channel has been studied. The results obtained indicate that the cytosolic protein is a substrate for cAMP-dependent phosphorylation. Polyamines at a concentration of 5.0 mmol/l inhibit markedly phosphorylation of the cytosolic protein. Spermine is shown to be the most effective inhibitor. It is suggested that polyamines may modulate the cell sodium channel function.
|
| pubmed:language |
rus
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0028-2561
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
603-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1664913-Animals,
pubmed-meshheading:1664913-Biogenic Polyamines,
pubmed-meshheading:1664913-Brain,
pubmed-meshheading:1664913-Cattle,
pubmed-meshheading:1664913-Cyclic AMP,
pubmed-meshheading:1664913-Cytosol,
pubmed-meshheading:1664913-Membrane Potentials,
pubmed-meshheading:1664913-Phosphorylation,
pubmed-meshheading:1664913-Proteins,
pubmed-meshheading:1664913-Sodium Channels
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
[Polyamine modulation of phosphorylation of channel-forming cytosolic protein in bovine brain].
|
| pubmed:publicationType |
Journal Article,
English Abstract
|