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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-5-1
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pubmed:abstractText |
Whole brain irradiation (WBRT) remains a recommended treatment for patients with brain metastases from malignant melanoma in terms of symptom palliation, especially when extracranial systemic disease is present. Temozolomide (TMZ) has shown efficacy in the treatment of metastatic melanoma. The objective was to evaluate the potential benefit in survival of two different schedules of total dose and fractionation (20 Gy/5 fractions vs 30 Gy/10 fractions) and further TMZ based chemotherapy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1699-048X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
266-70
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16648102-Adult,
pubmed-meshheading:16648102-Aged,
pubmed-meshheading:16648102-Antineoplastic Agents, Alkylating,
pubmed-meshheading:16648102-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16648102-Brain Neoplasms,
pubmed-meshheading:16648102-Cisplatin,
pubmed-meshheading:16648102-Cohort Studies,
pubmed-meshheading:16648102-Combined Modality Therapy,
pubmed-meshheading:16648102-Cranial Irradiation,
pubmed-meshheading:16648102-Dacarbazine,
pubmed-meshheading:16648102-Drug Administration Schedule,
pubmed-meshheading:16648102-Drug Evaluation,
pubmed-meshheading:16648102-Female,
pubmed-meshheading:16648102-Humans,
pubmed-meshheading:16648102-Interferon-alpha,
pubmed-meshheading:16648102-Interleukin-2,
pubmed-meshheading:16648102-Life Tables,
pubmed-meshheading:16648102-Male,
pubmed-meshheading:16648102-Melanoma,
pubmed-meshheading:16648102-Middle Aged,
pubmed-meshheading:16648102-Patient Selection,
pubmed-meshheading:16648102-Proportional Hazards Models,
pubmed-meshheading:16648102-Recombinant Proteins,
pubmed-meshheading:16648102-Retrospective Studies,
pubmed-meshheading:16648102-Survival Analysis,
pubmed-meshheading:16648102-Treatment Outcome,
pubmed-meshheading:16648102-Vinblastine
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pubmed:year |
2006
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pubmed:articleTitle |
Whole brain irradiation and temozolomide based chemotherapy in melanoma brain metastases.
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pubmed:affiliation |
Department of Radiation Oncology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. cconill@clinic.ub.es
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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