Source:http://linkedlifedata.com/resource/pubmed/id/16647845
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
2006-5-22
|
pubmed:abstractText |
X chromosome inactivation represents a compelling example of chromosome-wide, long-range epigenetic gene-silencing in mammals. The cis- and trans-acting factors that establish and maintain the patterns and levels of gene expression from the active and inactive X chromosomes remain incompletely understood; however, the availability of the complete genomic sequence of the human X chromosome, together with complementary approaches that explore the computational biology, epigenetic modifications and gene expression-profiling along the chromosome, suggests that the features of the X chromosome that are responsible for its unique forms of gene regulation are increasingly amenable to experimental analysis.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0959-437X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
240-5
|
pubmed:meshHeading |
pubmed-meshheading:16647845-Animals,
pubmed-meshheading:16647845-Epigenesis, Genetic,
pubmed-meshheading:16647845-Genomics,
pubmed-meshheading:16647845-Heterochromatin,
pubmed-meshheading:16647845-Humans,
pubmed-meshheading:16647845-X Chromosome,
pubmed-meshheading:16647845-X Chromosome Inactivation
|
pubmed:year |
2006
|
pubmed:articleTitle |
Genomic and epigenomic approaches to the study of X chromosome inactivation.
|
pubmed:affiliation |
Institute for Genome Sciences & Policy, Duke University, 101 Science Drive, CIEMAS 2376, Durham, NC 27708, USA.
|
pubmed:publicationType |
Journal Article,
Review
|