| pubmed-article:1664344 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1664344 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:1664344 | lifeskim:mentions | umls-concept:C0020964 | lld:lifeskim |
| pubmed-article:1664344 | lifeskim:mentions | umls-concept:C0449438 | lld:lifeskim |
| pubmed-article:1664344 | lifeskim:mentions | umls-concept:C1519885 | lld:lifeskim |
| pubmed-article:1664344 | lifeskim:mentions | umls-concept:C0439234 | lld:lifeskim |
| pubmed-article:1664344 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:1664344 | pubmed:dateCreated | 1992-3-19 | lld:pubmed |
| pubmed-article:1664344 | pubmed:abstractText | A study of poliomyelitis neutralizing antibodies was carried out on 165 samples of blood serum drawn from subjects aged 14-15 years who had completed vaccination with OPV 11 or 12 years ago. Two different methods of incubation of the serum-virus mixtures (1 hour at 37 degrees C; 6 hours at 37 degrees C and then 18 hours at 4 degrees C, respectively) and two different cell lines (RC-37 and Hep-2) for the inoculation of these mixtures were employed. The results were also evaluated in relation to different initial dilutions of the sera (from 1:4 to 1:1). With the 1:4 initial serum dilution the highest frequencies of sero-negativity were observed utilizing the short incubation time and inoculation in Hep-2 (42% for polio 1, 10% for polio 2, 32% for polio 3). These frequencies diminish significantly utilizing the RC-37 cell line and the long incubation respectively. Under all the experimental conditions the results were better when the 1:2 initial serum dilutions were employed and even better when undiluted sera were used. Neutralizing antibodies against the 3 types of poliovirus were detected in the undiluted sera of all the subjects utilizing the long incubation and inoculation in either the RC-37 or the Hep-2 cell lines. In three subjects lacking detectable antibodies at the 1:4 dilution of the sera, the administration of a dose of IPV produced after 5-7 days a high response which remained almost unchanged 30 days later. | lld:pubmed |
| pubmed-article:1664344 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1664344 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1664344 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1664344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1664344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1664344 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1664344 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1664344 | pubmed:issn | 0393-2990 | lld:pubmed |
| pubmed-article:1664344 | pubmed:author | pubmed-author:BellelliEE | lld:pubmed |
| pubmed-article:1664344 | pubmed:author | pubmed-author:BracchiUU | lld:pubmed |
| pubmed-article:1664344 | pubmed:author | pubmed-author:TanziM LML | lld:pubmed |
| pubmed-article:1664344 | pubmed:author | pubmed-author:AffanniPP | lld:pubmed |
| pubmed-article:1664344 | pubmed:author | pubmed-author:BocelliVV | lld:pubmed |
| pubmed-article:1664344 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1664344 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:1664344 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1664344 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1664344 | pubmed:pagination | 605-11 | lld:pubmed |
| pubmed-article:1664344 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:meshHeading | pubmed-meshheading:1664344-... | lld:pubmed |
| pubmed-article:1664344 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1664344 | pubmed:articleTitle | Antipoliomyelitis immunity status among a population that was regularly vaccinated 11-12 years before. | lld:pubmed |
| pubmed-article:1664344 | pubmed:affiliation | Istituto di Igiene, Università degli Studi di Parma, Italy. | lld:pubmed |
| pubmed-article:1664344 | pubmed:publicationType | Journal Article | lld:pubmed |
