Source:http://linkedlifedata.com/resource/pubmed/id/16643051
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2006-4-28
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pubmed:abstractText |
Chromatographic investigation of an acetone extract of the octocoral Xenia florida afforded three new xenicane diterpenes, namely, florxenilide A (1), florxenilide B (2), and florxenilide C (3), in addition to seven known xenicane diterpenes and two known cadinene sesquiterpenes. Structures were elucidated through spectroscopic analysis, especially 2D NMR, and chemical derivatization. The absolute configuration of 1 was determined by NOESY, CD, and Mosher's methods. Florxenilides A (1) and B (2) exhibited cytotoxicity against human colon cancer (WiDr) cells at 4.5 and 3.7 muM, respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
675-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16643051-Animals,
pubmed-meshheading:16643051-Anthozoa,
pubmed-meshheading:16643051-Antineoplastic Agents,
pubmed-meshheading:16643051-Diterpenes,
pubmed-meshheading:16643051-Drug Screening Assays, Antitumor,
pubmed-meshheading:16643051-Humans,
pubmed-meshheading:16643051-Molecular Structure,
pubmed-meshheading:16643051-Sesquiterpenes,
pubmed-meshheading:16643051-Taiwan,
pubmed-meshheading:16643051-Tumor Cells, Cultured
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pubmed:year |
2006
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pubmed:articleTitle |
Xenicane-type diterpenes with cytotoxicity from Xenia florida.
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pubmed:affiliation |
Institute of Marine Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung, Taiwan 80424, Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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