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rdf:type |
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lifeskim:mentions |
umls-concept:C0019564,
umls-concept:C0038435,
umls-concept:C0051318,
umls-concept:C0072899,
umls-concept:C0205178,
umls-concept:C0442805,
umls-concept:C0871261,
umls-concept:C1167622,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
1
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pubmed:dateCreated |
1992-3-19
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pubmed:abstractText |
The binding properties of ligands specific for two subclasses of glutamate receptors were studied by quantitative autoradiography after one hour of acute immobilization/shock stress. [3H]N-(1-(2-thienyl)cyclohexyl)-3,4-piperidine (TCP) and [3H]alpha-amino-3-methylisoxazole-4-propionic acid (AMPA) were used to visualize the N-methyl-D-aspartate receptor and the AMPA/quisqualate receptor types, respectively. While no change was observed in the binding properties of the [3H]TCP, [3H]AMPA binding was significantly increased in several areas of the hippocampus of acutely stressed rats relative to naive controls.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0006-8993
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
559
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
168-71
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1664274-Animals,
pubmed-meshheading:1664274-Autoradiography,
pubmed-meshheading:1664274-Electroshock,
pubmed-meshheading:1664274-Hippocampus,
pubmed-meshheading:1664274-Ibotenic Acid,
pubmed-meshheading:1664274-Phencyclidine,
pubmed-meshheading:1664274-Rats,
pubmed-meshheading:1664274-Receptors, AMPA,
pubmed-meshheading:1664274-Receptors, N-Methyl-D-Aspartate,
pubmed-meshheading:1664274-Receptors, Neurotransmitter,
pubmed-meshheading:1664274-Restraint, Physical,
pubmed-meshheading:1664274-Stress, Psychological,
pubmed-meshheading:1664274-Synaptic Transmission,
pubmed-meshheading:1664274-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
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pubmed:year |
1991
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pubmed:articleTitle |
Selective increase of AMPA binding to the AMPA/quisqualate receptor in the hippocampus in response to acute stress.
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pubmed:affiliation |
Neurosciences Program, University of Southern California, Los Angeles 90089-2520.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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